See the DrugPatentWatch profile for aspirin

Based on the available information, individuals who should avoid taking aspirin before sleeping include:

1. People with a known allergy or hypersensitivity to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) [1].
2. Those with a history of gastrointestinal ulcers or bleeding, as aspirin can increase the risk of gastrointestinal bleeding [1].
3. People with liver or kidney disease, as aspirin can affect liver function and kidney function [1].
4. Individuals with uncontrolled hypertension or heart disease, as aspirin can affect blood pressure and increase the risk of heart attack or stroke [1].
5. People taking other medications that can interact with aspirin, such as blood thinners, corticosteroids, and selective serotonin reuptake inhibitors (SSRIs) [1].
6. Pregnant women or those breastfeeding, as aspirin can affect fetal development and pass through breast milk [1].
7. Children and teenagers with viral infections, as aspirin has been linked to Reye's syndrome, a rare but serious condition that can cause liver and brain damage [1].

It's important to note that this list is not exhaustive, and individuals should consult with their healthcare provider before taking aspirin or any other medication.

Sources:

1. DrugPatentWatch.com. (n.d.). Aspirin. Retrieved from <https://www.drugpatentwatch.com/drugs/aspirin>