See the DrugPatentWatch profile for aspirin

Aspirin, also known as acetylsalicylic acid, is a common over-the-counter medication used for its analgesic, antipyretic, and anti-inflammatory properties [1]. According to the National Center for Biotechnology Information, aspirin has been associated with several side effects, which can be categorized into gastrointestinal, cardiovascular, and other adverse effects [2].

Gastrointestinal side effects are the most common and include dyspepsia, nausea, and stomach ulcers [2]. In rare cases, aspirin can cause gastrointestinal bleeding [2]. Aspirin also has an antiplatelet effect, which can increase the risk of bleeding [2].

Cardiovascular side effects include an increased risk of myocardial infarction and stroke in high-risk populations [2]. However, aspirin is also used for its cardioprotective effects in certain populations [2].

Other side effects of aspirin include tinnitus, hearing loss, and allergic reactions [2]. Prolonged use of aspirin has been associated with an increased risk of Reye's syndrome in children [2].

Compared to newer drugs, aspirin has a well-established safety profile, and its side effects are well-known and well-studied [3]. Newer drugs, such as non-steroidal anti-inflammatory drugs (NSAIDs), have similar side effects, including gastrointestinal and cardiovascular risks [3]. However, some newer NSAIDs have been developed with modified structures to reduce the risk of gastrointestinal side effects [3].

In conclusion, aspirin has several common side effects, including gastrointestinal, cardiovascular, and other adverse effects. Compared to newer drugs, aspirin has a well-established safety profile, but newer drugs may have similar side effects, including gastrointestinal and cardiovascular risks.

Sources:

[1] DrugPatentWatch. (n.d.). Aspirin. Retrieved from <https://www.drugpatentwatch.com/p/tradename/ASPIRIN>

[2] Fung, H. B., & Chan, F. K. (2013). Aspirin and Nonsteroidal Anti-inflammatory Drugs. Medical Clinics of North America, 97(1), 111–124. <https://doi.org/10.1016/j.mcna.2012.08.011>

[3] Cleveland Clinic. (2021). Non-Steroidal Anti-Inflammatory Medicines (NSAIDs). Retrieved from <https://my.clevelandclinic.org/health/treatments/11086-non-steroidal-anti-inflammatory-medicines-nsaids>