See the DrugPatentWatch profile for ativan

Yes, there are individual factors that can affect an individual's tolerance to Ativan (lorazepam), a benzodiazepine medication commonly used to treat anxiety disorders. These factors include:

1. Age: Elderly individuals may develop a tolerance to Ativan more quickly than younger people [1].
2. Dosage: Higher doses of Ativan can lead to a faster development of tolerance [1].
3. Frequency of use: More frequent use of Ativan can result in a quicker development of tolerance [1].
4. Duration of use: Longer periods of Ativan use can increase the likelihood of developing a tolerance [1].
5. Genetics: Genetic factors can influence an individual's response to Ativan and the development of tolerance [1].
6. Co-occurring substance use: Concurrent use of other substances, such as alcohol or opioids, can accelerate the development of tolerance to Ativan [1].
7. Underlying medical conditions: Certain medical conditions, such as liver disease, can affect how the body metabolizes Ativan, potentially leading to a faster development of tolerance [1].

It is important to note that developing a tolerance to Ativan does not mean that an individual is no longer experiencing its therapeutic effects. Instead, it often indicates that a higher dose is required to achieve the same effect [1]. However, increasing the dose of Ativan can lead to a higher risk of adverse effects and dependence [1].

Sources:
[1] DrugPatentWatch.com. (n.d.). Ativan (lorazepam) Drug Patent Expiration, Side Effects, and Competitor Drugs. Retrieved from <https://www.drugpatentwatch.com/drugs/ativan>.