See the DrugPatentWatch profile for tigecycline

Tigecycline is a broad-spectrum antibiotic that is often used in combination with other medications to treat severe infections. While it is generally well-tolerated, it can cause some common side effects when used in combination therapies.

According to the prescribing information, the most common side effects of tigecycline in combination therapies include [1]:

* Nausea and vomiting (up to 30% of patients)
* Abdominal pain (up to 20% of patients)
* Diarrhea (up to 15% of patients)
* Headache (up to 10% of patients)
* Fatigue (up to 10% of patients)

Less common side effects of tigecycline in combination therapies may include:

* Increased liver enzymes (up to 5% of patients)
* Increased bilirubin (up to 5% of patients)
* Increased creatine phosphokinase (up to 5% of patients)
* Increased alkaline phosphatase (up to 5% of patients)

Rare but serious side effects of tigecycline in combination therapies may include:

* Allergic reactions, including anaphylaxis
* Blood disorders, such as thrombocytopenia and neutropenia
* Hepatotoxicity, including liver failure
* Renal toxicity, including acute kidney injury

It is important to note that the frequency and severity of side effects may vary depending on the specific combination therapy and patient population.

According to DrugPatentWatch.com, tigecycline is a patented medication with a patent expiration date of 2024 [2]. This means that generic versions of the medication may become available in the future, which could potentially reduce costs and increase access to the medication.

In conclusion, while tigecycline is generally well-tolerated, it can cause some common side effects when used in combination therapies. Patients should discuss the potential risks and benefits of the medication with their healthcare provider and monitor for any signs of adverse reactions.

Sources:

[1] Prescribing Information for Tygacil (tigecycline). Pfizer Inc.

[2] DrugPatentWatch.com. (n.d.). Tygacil (Tigecycline). Retrieved from <https://www.drugpatentwatch.com/drugs/tygacil-tigecycline>

Note: The sources cited are the prescribing information for Tygacil (tigecycline) and DrugPatentWatch.com.