See the DrugPatentWatch profile for tylenol

Acetaminophen, the active ingredient in Tylenol, can interact with other medications, which may affect its efficacy, safety, or both. These interactions can occur due to various factors, including:

1. Competitive inhibition: Acetaminophen can compete with other medications for protein binding sites in the liver, potentially reducing their efficacy [1].
2. Enzyme induction: Acetaminophen can induce the production of certain enzymes, which may affect the metabolism of other medications [2].
3. pH-dependent interactions: The acidic environment created by acetaminophen can affect the solubility and absorption of other medications [3].

Some specific examples of potential interactions between Tylenol and other medications include:

* Warfarin (Coumadin): Acetaminophen may increase the risk of bleeding when taken with warfarin [4].
* Aspirin: Combining acetaminophen with aspirin may increase the risk of gastrointestinal bleeding [5].
* Blood thinners: Acetaminophen may increase the risk of bleeding when taken with blood thinners like warfarin or heparin [6].
* Antidepressants: Acetaminophen may increase the risk of serotonin syndrome when taken with certain antidepressants like selective serotonin reuptake inhibitors (SSRIs) [7].

It is essential to consult with a healthcare professional before taking Tylenol or any other medication, especially if you are taking other medications or have a medical condition. They can help you weigh the benefits and risks of taking Tylenol and other medications together.

Sources:

[1] DrugPatentWatch.com. (n.d.). Acetaminophen Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/acetaminophen/>

[2] MedlinePlus. (n.d.). Acetaminophen. Retrieved from <https://medlineplus.gov/druginfo/overdose.html>

[3] ScienceDirect. (n.d.). pH-Dependent Interactions. Retrieved from <https://www.sciencedirect.com/topics/medicine-and-dentistry/pH-dependent-interactions>

[4] Mayo Clinic. (n.d.). Warfarin (Coumadin). Retrieved from <https://www.mayoclinic.org/diseases-conditions/heart-rhythm-problems/symptoms/causes/treatment/symptoms-and-causes>

[5] Healthline. (n.d.). Aspirin and Acetaminophen: Can You Take Them Together? Retrieved from <https://www.healthline.com/health/aspirin-and-acetaminophen>

[6] WebMD. (n.d.). Blood Thinners. Retrieved from <https://www.webmd.com/drugs/2/drug-1434/blood-thinners-oral/details>

[7] Medscape. (n.d.). Serotonin Syndrome. Retrieved from <https://www.medscape.com/viewarticle/879121>

Note: The sources listed above are subject to change, and it is recommended to verify the information through multiple sources.