See the DrugPatentWatch profile for lipitor

Based on the information available, there is no definitive answer to how often patients experience liver damage while taking Lipitor (atorvastatin). Lipitor is a statin medication used to lower cholesterol levels, and while it is generally well-tolerated, it can have side effects, including liver damage [1]. However, the frequency of this side effect is not explicitly stated in the sources.

The U.S. Food and Drug Administration (FDA) requires that Lipitor's label includes a warning about the potential for liver damage [2]. The label states that "increases in transaminases can occur during treatment with statins, including Lipitor. These changes are usually transient and rarely require interruption of therapy" [2]. However, the label does not provide specific statistics on the occurrence of liver damage.

A study published in the Journal of Clinical Pharmacy and Therapeutics analyzed data from the FDA's Adverse Event Reporting System (FAERS) to identify adverse events associated with statins, including Lipitor [3]. The study found that "hepatic and biliary disorders" were reported for all statins, including Lipitor. However, the study did not provide specific statistics on the frequency of liver damage associated with Lipitor.

In summary, while Lipitor can cause liver damage, the frequency of this side effect is not explicitly stated in the available information. It is essential to consult with a healthcare provider to discuss the potential risks and benefits of any medication.

Sources:

1. Mayo Clinic. Lipitor (Atorvastatin). <https://www.mayoclinic.org/drugs-supplements/lipitor-oral-route/side-effects/drg-20068855>.
2. U.S. Food and Drug Administration. Lipitor (Atorvastatin Calcium) Tablets, for Oral Use. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020288s052lbl.pdf>.
3. Haubenhofer, S., & Wuppermann, N. (2012). Statins and adverse drug reactions: a disproportionality analysis of the FDA's adverse event reporting system (FAERS). Journal of clinical pharmacy and therapeutics, 37(3), 255-261. <https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2710.2012.01361.x>.
4. DrugPatentWatch.com. Lipitor (Atorvastatin) Drug Profile. <https://www.drugpatentwatch.com/drugs/lipitor>.