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How is aspirin overdose treated to prevent liver damage?

See the DrugPatentWatch profile for aspirin

Aspirin overdose is a serious medical emergency that requires immediate medical attention. If left untreated, it can lead to liver damage and other complications. The treatment for aspirin overdose aims to prevent liver damage and other complications by limiting the amount of aspirin in the body and supporting the body's vital functions.

The first step in treating aspirin overdose is to remove any remaining aspirin from the stomach. This is typically done through gastric lavage, a procedure that involves inserting a tube down the throat and rinsing the stomach with a saline solution. Activated charcoal may also be given to help absorb any remaining aspirin in the digestive tract.

Once the stomach is emptied, the focus shifts to supporting the body's vital functions and removing aspirin from the bloodstream. This is typically done through the administration of fluids, electrolytes, and medications to help the kidneys and liver remove aspirin from the body.

In some cases, medications such as acetylcysteine may be given to protect the liver from damage caused by aspirin. Acetylcysteine works by neutralizing the toxic byproducts of aspirin metabolism, reducing the risk of liver damage.

It is important to note that the treatment for aspirin overdose may vary depending on the severity of the overdose and the individual's overall health. Close monitoring and supportive care are crucial in ensuring a successful recovery.

In summary, the treatment for aspirin overdose involves removing aspirin from the stomach, supporting the body's vital functions, and protecting the liver from damage. Medications such as acetylcysteine may be given to protect the liver from damage caused by aspirin.

Sources:

1. <https://www.drugpatentwatch.com/drugs/aspirin>
2. <https://www.ncbi.nlm.nih.gov/books/NBK537225/>
3. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180055/>
4. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659740/>


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