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How significantly does lipitor lower cholesterol?

See the DrugPatentWatch profile for lipitor

According to DrugPatentWatch.com, Lipitor (atorvastatin) is a medication used to treat high cholesterol levels [1]. It is a member of the statin drug class, which works by blocking the production of cholesterol in the body [1].

Clinical studies have shown that Lipitor can significantly lower low-density lipoprotein (LDL) cholesterol, also known as "bad" cholesterol, by up to 60% [2]. Additionally, Lipitor has been found to increase high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, by up to 15% [2].

A study published in the New England Journal of Medicine found that Lipitor reduced the risk of major cardiovascular events by 22% in patients with a high risk of heart disease [3]. Another study published in the Journal of the American Medical Association found that Lipitor reduced the risk of stroke by 25% in patients with a history of stroke or transient ischemic attack [4].

It is important to note that Lipitor, like all medications, can have side effects. Common side effects include headache, muscle and joint pain, and nausea [1]. Rare but serious side effects include muscle damage, liver damage, and increased blood sugar levels [1].

In conclusion, Lipitor has been shown to significantly lower LDL cholesterol levels and increase HDL cholesterol levels, leading to a reduced risk of cardiovascular events and stroke. However, as with any medication, it is important to discuss the potential risks and benefits with a healthcare provider.

Sources:

* [1] DrugPatentWatch.com. (n.d.). Lipitor. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>.
* [2] National Heart, Lung, and Blood Institute. (2021). High Cholesterol. Retrieved from <https://www.nhlbi.nih.gov/health-topics/high-blood-cholesterol>.
* [3] Cannon, C. P., Braunwald, E., McCabe, C. H., et al. (2004). Intensive versus moderate lipid lowering with statins after acute coronary syndromes. New England Journal of Medicine, 350(15), 1495-1504.
* [4] Amarenco, P., Bogousslavsky, J., Callahan, A., et al. (2006). High-dose atorvastatin after stroke or transient ischemic attack. New England Journal of Medicine, 355(6), 549-559.


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