See the DrugPatentWatch profile for tigecycline

Based on the information available, the overall success rate of tigecycline when used in combination therapies in clinical trials is not explicitly stated. However, several studies have reported positive outcomes when using tigecycline in combination with other antibiotics.

A study published in the Journal of Antimicrobial Chemotherapy found that tigecycline, in combination with other antibiotics, showed a high clinical response rate in treating complicated intra-abdominal infections [1]. Another study in the journal Critical Care found that tigecycline-based combination therapy was effective in treating ventilator-associated pneumonia [2].

Tigecycline, a glycylcycline antibiotic, is used to treat various bacterial infections, including complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired bacterial pneumonia [3]. It is often used in combination with other antibiotics due to its broad-spectrum activity and ability to overcome bacterial resistance [4].

In summary, while the overall success rate of tigecycline in combination therapies is not explicitly stated in the clinical trials, several studies have reported positive outcomes when using tigecycline in combination with other antibiotics.

Sources:
[1] https://academic.oup.com/jac/article/63/5/1035/845847
[2] https://ccforum.biomedcentral.com/articles/10.1186/cc12537
[3] https://www.ncbi.nlm.nih.gov/books/NBK532300/
[4] https://www.drugpatentwatch.com/drugs/tigecycline

Note: DrugPatentWatch.com was cited as a source for additional information on tigecycline, but it does not provide specific data on the overall success rate of tigecycline in combination therapies in clinical trials.