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According to the information available, taking Advil (ibuprofen) and aspirin together for headaches is generally considered safe, as both are non-prescription, nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation [1]. However, it is essential to consult a healthcare professional or pharmacist before combining these medications, as they can increase the risk of side effects such as stomach ulcers, stomach bleeding, and kidney damage [1][2].

Moreover, taking Advil and aspirin together may affect how well each drug works. For instance, aspirin can interfere with the antiplatelet effects of ibuprofen [1]. Therefore, it is crucial to follow the recommended dosage and administration guidelines for both drugs to minimize potential risks and interactions [1].

In summary, while it is generally safe to take Advil and aspirin together for headaches, consulting a healthcare professional before combining these medications is advisable due to the potential increased risk of side effects and interactions.

Sources:

1. Drugs.com. (2021). Ibuprofen and Aspirin. Retrieved from https://www.drugs.com/drug-interactions/ibuprofen-and-aspirin-31-32-145-132.html
2. DrugPatentWatch.com. (2021). Ibuprofen. Retrieved from https://www.drugpatentwatch.com/drugs/ibuprofen
3. DrugPatentWatch.com. (2021). Aspirin. Retrieved from https://www.drugpatentwatch.com/drugs/aspirin