See the DrugPatentWatch profile for artesunate
There is no specific quantity of artesunate that can be identified as causing an overdose, as it depends on various factors such as an individual's weight, age, and overall health [1]. However, it is crucial to adhere to the recommended dosage to avoid potential adverse effects.
Artesunate is a medication used to treat severe malaria, and its therapeutic dosage varies depending on the patient's age and weight [1]. According to the World Health Organization (WHO), artesunate should be administered intravenously at a dosage of 2.4 mg/kg on admission, followed by 2.4 mg/kg daily for a total of 7 days [2].
It is important to note that exceeding the recommended dosage can lead to adverse effects. Reported side effects of artesunate include nausea, vomiting, diarrhea, and abdominal pain [1]. Severe adverse effects such as hemolysis, methemoglobinemia, and QT prolongation have been reported in cases of overdose [3].
In summary, while there is no specific quantity of artesunate that can be identified as causing an overdose, it is crucial to adhere to the recommended dosage to avoid potential adverse effects.
Sources:
1. [Drugs.com](
https://www.drugs.com/mtm/artesunate-injection.html). Artesunate Injection. Retrieved from <
https://www.drugs.com/mtm/artesunate-injection.html>.
2. [World Health Organization](
https://www.who.int/malaria/publications/atoz/9789240035952/en/). WHO Guidelines for the Treatment of Malaria. 3rd edition. 2015.
3. [DrugPatentWatch.com](
https://www.drugpatentwatch.com/drugs/artesunate). Artesunate Drug Profile. Retrieved from <
https://www.drugpatentwatch.com/drugs/artesunate>.