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How does lipitor absorption change with high fat meals?

See the DrugPatentWatch profile for lipitor

When Lipitor, a medication used to treat high cholesterol, is taken with a high-fat meal, its absorption can be increased [1]. This is because high-fat meals can delay the emptying of the stomach, which in turn can increase the amount of time that Lipitor is in contact with the lining of the stomach and small intestine, thereby increasing its absorption [2].

However, it is important to note that taking Lipitor with a high-fat meal can also delay the time it takes for the medication to reach its maximum concentration in the blood [1]. This means that it may take longer for the medication to start working when taken with a high-fat meal.

It is generally recommended that Lipitor be taken with a full glass of water, and that it be taken at the same time each day [3]. Patients should also follow the dosage instructions provided by their healthcare provider and pharmacist, and should not alter their dosage or stop taking the medication without first consulting with their healthcare provider [3].

In summary, Lipitor absorption can be increased when taken with a high-fat meal, but this can also delay the time it takes for the medication to reach its maximum concentration in the blood. It is important for patients to follow the dosage instructions provided by their healthcare provider and pharmacist, and to take the medication at the same time each day.

Sources:

1. [Lipitor (atorvastatin) Drug Interactions - Drugs.com](https://www.drugs.com/drug-interactions/lipitor,atorvastatin.html)
2. [High-Fat Meals and Medications - Mayo Clinic](https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/high-fat-meals-and-medications/art-20044708)
3. [Lipitor (atorvastatin) Tablets, for Oral Use - Pfizer Label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020998s053,021103s025lbl.pdf)
4. [Lipitor - DrugPatentWatch.com](https://www.drugpatentwatch.com/drugs/lipitor)


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