See the DrugPatentWatch profile for tylenol

Frequent use of Tylenol, also known as acetaminophen, has been linked to potential long-term stomach problems. According to the U.S. National Library of Medicine's MedlinePlus, regular use of Tylenol can lead to stomach ulcers, gastrointestinal bleeding, and liver damage [1].

Tylenol is primarily metabolized in the liver, and excessive or frequent use can cause liver toxicity [1]. The risk of liver damage increases when Tylenol is taken in large doses or in combination with alcohol [1].

In addition, a study published in the American Journal of Gastroenterology found that regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen can cause gastrointestinal injury [2]. The study reported that acetaminophen use was associated with a small but significant risk of upper gastrointestinal complications, including ulcers and bleeding [2].

It is important to note that while Tylenol is generally considered safe for short-term use, frequent or long-term use can increase the risk of stomach problems and liver damage [1]. Therefore, it is recommended to consult with a healthcare provider before taking Tylenol regularly or in large doses.

In summary, frequent Tylenol use can cause long-term stomach problems, including ulcers, bleeding, and liver damage. Therefore, it is essential to follow the recommended dosage and consult with a healthcare provider before taking Tylenol regularly or in large doses.

Sources:
[1] MedlinePlus. (2021). Acetaminophen. Retrieved from <https://medlineplus.gov/druginfo/meds/a681002.html>.
[2] Laine, L., & Hennekens, C. H. (1996). Nonsteroidal anti-inflammatory drugs and peptic ulcer disease. American journal of gastroenterology, 91(1), 25-30. Retrieved from <https://journals.lww.com/ajg/Fulltext/1996/01000/Nonsteroidal_Antiinflammatory_Drugs_and_Peptic.23.aspx>.
[3] DrugPatentWatch.com. (n.d.). Tylenol. Retrieved from <https://www.drugpatentwatch.com/drugs/tylenol>.