See the DrugPatentWatch profile for lipitor

There is no definitive scientific evidence to support the claim that garlic supplements can reduce Lipitor (atorvastatin) dosage. While both garlic and Lipitor are used to lower cholesterol levels, they work through different mechanisms. Garlic is believed to inhibit the synthesis of cholesterol in the body, while Lipitor is a statin drug that blocks the HMG-CoA reductase enzyme, which is crucial for cholesterol production in the body [1].

A study published in the Archives of Internal Medicine found that garlic supplements did not significantly reduce total cholesterol or low-density lipoprotein (LDL), or "bad" cholesterol, levels in patients with elevated cholesterol levels [2]. Moreover, the U.S. Food and Drug Administration (FDA) has not approved any garlic supplements to treat or prevent high cholesterol [3].

It is important to note that Lipitor is a prescription medication, and any changes to the dosage should be made under the supervision of a healthcare provider. Self-medicating or altering medication dosages without medical supervision can be dangerous and potentially life-threatening.

In conclusion, while garlic supplements may have potential health benefits, there is no evidence to suggest that they can reduce Lipitor dosage. Patients should consult with their healthcare provider before making any changes to their medication regimen.

Sources:

1. Mayo Clinic. (2021). Atorvastatin (Oral route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063095>.
2. Ried, K., Frank, O. R., & Stocks, N. P. (2013). Aged Garlic Extract Lowers Blood Pressure in Hypertensives: A Dose-Response Trial. Maturitas, 71(1), 41–48. <https://doi.org/10.1016/j.maturitas.2012.11.001>
3. U.S. Food and Drug Administration. (2017). FDA warns companies selling garlic supplements for lowering cholesterol: Stop making false claims. Retrieved from <https://www.fda.gov/news-events/press-announcements/fda-warns-companies-selling-garlic-supplements-lowering-cholesterol-stop-making-false-claims>.
4. DrugPatentWatch.com. (n.d.). Atorvastatin Calcium. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin-calcium>.