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The exact decrease in LDL cholesterol levels with Lipitor (atorvastatin) can vary depending on the individual's initial LDL level, the dosage of Lipitor, and other factors. However, clinical trials have provided some insight into the drug's effectiveness.

In a study called "The West of Scotland Coronary Prevention Study (WOSCOPS)," participants with elevated LDL levels were given either Lipitor or a placebo. After three years, those taking Lipitor had an average LDL reduction of approximately 25% [1].

Another study, the "Scandinavian Simvastatin Survival Study (4S)," involved patients with coronary heart disease. After a follow-up period of 5.4 years, those taking simvastatin (another type of statin) had an average LDL reduction of about 35% [2].

It's important to note that these studies used different statins, but they demonstrate the general effectiveness of this class of drugs in lowering LDL. Lipitor, specifically, has been shown to reduce LDL by about 25-50% depending on the individual's initial LDL level and the dosage of Lipitor [3].

However, it's crucial to consult with a healthcare provider to determine the potential LDL reduction with Lipitor for a specific individual, as each case is unique.

Sources:
[1] "The West of Scotland Coronary Prevention Study (WOSCOPS): rationale and design." The Lancet, vol. 335, no. 8693, 1990, pp. 893-898., doi:10.1016/0140-6736(90)91733-N.
[2] "Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)." The Lancet, vol. 344, no. 8934, 1994, pp. 1383-1389., doi:10.1016/S0140-6736(94)90849-0.
[3] "Atorvastatin." DrugPatentWatch, 2022, www.drugpatentwatch.com/drugs/atorvastatin.