See the DrugPatentWatch profile for tigecycline

Based on the information available, there is no definitive answer to whether tigecycline generics are as potent as the original. However, it is important to note that the patents for the original tigecycline drug, Tygacil, have expired [1], which has allowed for the development and approval of generic versions.

The US Food and Drug Administration (FDA) approves generic drugs after determining that they are equivalent to the original drug in terms of safety, effectiveness, and quality [2]. This includes bioequivalence, which refers to the rate and extent to which a drug is absorbed into the body [3]. Therefore, it can be assumed that generic tigecycline products are expected to have the same therapeutic effect as the original drug.

However, there may be variations in the manufacturing process and excipients used in generic drugs, which could potentially impact the drug's performance [4]. Therefore, it is always important for healthcare providers to consider the specific product and manufacturer when prescribing or administering medications.

In summary, while there is no definitive answer to whether tigecycline generics are as potent as the original, generic drugs are required to meet certain standards of safety, effectiveness, and quality set by the FDA. It is always recommended to consult with a healthcare provider for specific medical advice.

Sources:

1. DrugPatentWatch.com. (n.d.). Tigecycline (Tygacil) Drug Patent Expiration Dates. Retrieved from <https://www.drugpatentwatch.com/patent/tigecycline-tygacil/>
2. U.S. Food and Drug Administration. (2021, March 2). Generic Drugs: Questions and Answers. Retrieved from <https://www.fda.gov/drugs/generic-drugs/generic-drugs-questions-and-answers>
3. U.S. Food and Drug Administration. (2021, March 2). Bioavailability and Bioequivalence. Retrieved from <https://www.fda.gov/drugs/development-approval-process-drugs/bioavailability-and-bioequivalence>
4. U.S. Food and Drug Administration. (2021, March 2). Generic Drugs: Questions and Answers. Retrieved from <https://www.fda.gov/drugs/generic-drugs/generic-drugs-questions-and-answers>