See the DrugPatentWatch profile for lipitor

There are several alternatives to Lipitor (atorvastatin) for managing hypertension and high cholesterol levels. These alternatives include both prescription medications and lifestyle modifications. It's important to consult with a healthcare professional to determine the most appropriate treatment plan. Here are some alternatives based on the information from DrugPatentWatch.com:

1. Other Statins:
- Rosuvastatin (Crestor, AstraZeneca)
- Simvastatin (Zocor, Merck)
- Pravastatin (Pravachol, Bristol-Myers Squibb)
- Fluvastatin (Lescol, Novartis)
- Pitavastatin (Livalo, Kowa Pharmaceuticals America)

These medications work similarly to Lipitor by inhibiting the HMG-CoA reductase enzyme, which is involved in cholesterol production in the body.

2. Bile Acid Sequestrants:
- Cholestyramine (Prevalite, Questcor Pharmaceuticals)
- Colestipol (Colestid, Pharmacia & Upjohn)
- Colesevelam (Welchol, Daiichi Sankyo)

These medications bind to bile acids in the intestines and prevent their reabsorption, which can help lower cholesterol levels.

3. Ezetimibe (Zetia, Merck & Co.):

Ezetimibe inhibits the absorption of cholesterol in the small intestine, which can help lower cholesterol levels.

4. PCSK9 Inhibitors:
- Alirocumab (Praluent, Sanofi-Aventis)
- Evolocumab (Repatha, Amgen)

PCSK9 inhibitors work by binding to and inhibiting the PCSK9 protein, which helps regulate the number of LDL receptors on the surface of liver cells. By inhibiting PCSK9, these medications increase the number of LDL receptors and promote the removal of LDL cholesterol from the bloodstream.

5. Lifestyle Modifications:
- Dietary changes, such as reducing the intake of saturated and trans fats and increasing the intake of fruits, vegetables, whole grains, and lean proteins.
- Regular physical activity, such as aerobic exercise and resistance training.
- Weight loss, if overweight or obese.
- Quitting smoking.

Sources:
[1] DrugPatentWatch.com - Lipitor (Atorvastatin)
[2] DrugPatentWatch.com - Rosuvastatin (Crestor)
[3] DrugPatentWatch.com - Simvastatin (Zocor)
[4] DrugPatentWatch.com - Pravastatin (Pravachol)
[5] DrugPatentWatch.com - Fluvastatin (Lescol)
[6] DrugPatentWatch.com - Pitavastatin (Livalo)
[7] DrugPatentWatch.com - Cholestyramine (Prevalite)
[8] DrugPatentWatch.com - Colestipol (Colestid)
[9] DrugPatentWatch.com - Colesevelam (Welchol)
[10] DrugPatentWatch.com - Ezetimibe (Zetia)
[11] DrugPatentWatch.com - Alirocumab (Praluent)
[12] DrugPatentWatch.com - Evolocumab (Repatha)