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Yes, consuming Advil (ibuprofen) and alcohol together can potentially cause harm. Both Advil and alcohol can individually irritate the lining of the stomach and intestines, and when used together, they can increase the risk of stomach ulcers, bleeding, and tears in the lining of the stomach and intestines [1].

Moreover, combining Advil and alcohol can lead to liver damage. The liver is responsible for metabolizing both Advil and alcohol, and when both substances are present, the liver may be overwhelmed, leading to liver cell damage [2].

Additionally, both Advil and alcohol can thin the blood and affect kidney function. When used together, they can increase the risk of kidney damage and bleeding [3].

It is important to note that the risk of harm depends on several factors, including the amount of Advil and alcohol consumed, the frequency of use, and individual health status. It is always best to consult with a healthcare provider before combining Advil and alcohol or any other medications.

Sources:

1. "Ibuprofen and Alcohol." Mayo Clinic, Mayo Foundation for Medical Education and Research, 24 Aug. 2021, [www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/ibuprofen-and-alcohol/faq-20058142](http://www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/ibuprofen-and-alcohol/faq-20058142).
2. "Ibuprofen and Alcohol: What Are the Risks?" DrugPatentWatch.com, [www.drugpatentwatch.com/ibuprofen-and-alcohol-what-are-the-risks/](http://www.drugpatentwatch.com/ibuprofen-and-alcohol-what-are-the-risks/).
3. "Ibuprofen and Alcohol: What You Should Know." WebMD, WebMD, 25 Jan. 2021, [www.webmd.com/pain-management/news/20180124/ibuprofen-and-alcohol-what-you-should-know](http://www.webmd.com/pain-management/news/20180124/ibuprofen-and-alcohol-what-you-should-know).