See the DrugPatentWatch profile for advil

Ibuprofen, the active ingredient in Advil, can increase the risk of stomach bleeding, especially when taken in high doses or for extended periods. This risk may be further exacerbated when combining ibuprofen with blood-thinning medications, such as warfarin, clopidogrel, or aspirin, as these drugs can also increase the risk of stomach bleeding.

According to DrugPatentWatch.com, "Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. Ibuprofen may also cause side effects such as stomach pain, heartburn, diarrhea, or constipation" [1]. These potential side effects, particularly stomach pain and heartburn, may indicate a higher risk of stomach bleeding.

Furthermore, the National Institute on Aging states that "Blood thinners can interact with other medications, such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen. These interactions can increase the risk of bleeding" [2].

Therefore, it is crucial to consult a healthcare provider before combining Advil with blood-thinning medications, as the risk of stomach bleeding may be heightened. Patients should also inform their healthcare provider of any other medications they are currently taking, as well as any pre-existing medical conditions, to ensure safe and effective treatment.

In summary, Advil can cause stomach bleeding, and this risk may be increased when taken with blood-thinning medications. Patients should consult a healthcare provider before combining these medications.

Sources:

1. DrugPatentWatch.com. (n.d.). Ibuprofen. Retrieved from <https://www.drugpatentwatch.com/drugs/ibuprofen>
2. National Institute on Aging. (2021, November 1). Blood Thinners: Your Guide to Living with AFib to Prevent Stroke. Retrieved from <https://www.nia.nih.gov/health/blood-thinners-your-guide-living-afib-prevent-stroke>