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Based on the information available, it is possible to take certain antidepressants with Advil, also known as ibuprofen, a non-prescription nonsteroidal anti-inflammatory drug (NSAID) [1]. However, it is essential to consult a healthcare provider or pharmacist before combining any medications, including antidepressants and over-the-counter drugs like Advil, as interactions can occur [1][2].

Some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), may increase the risk of bleeding when combined with NSAIDs like Advil [1]. This interaction is due to the effect of these antidepressants on platelet function and blood clotting [1].

When taking antidepressants with Advil, it is crucial to monitor for signs of increased bleeding, such as easy bruising or prolonged bleeding from cuts [1]. Additionally, it is essential to follow the recommended dosages for both medications to minimize the risk of adverse effects [1].

In summary, while it is possible to take certain antidepressants with Advil, consulting a healthcare provider or pharmacist before combining these medications is crucial due to the potential for increased bleeding risk [1][2].

Sources:

[1] "Ibuprofen Interactions." RxList, <https://www.rxlist.com/ibuprofen_drugs_herbs_supplements/interactions.htm>.

[2] "Antidepressant Drugs." National Institute on Aging, U.S. Department of Health and Human Services, 15 Nov. 2017, <https://www.nia.nih.gov/health/antidepressant-drugs>.

[3] "Antidepressant Medication." Mayo Clinic, Mayo Foundation for Medical Education and Research, 21 Nov. 2020, <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20046273>.

[4] "Antidepressants." DrugPatentWatch, <https://www.drugpatentwatch.com/drug/antidepressants.html>.