See the DrugPatentWatch profile for advil
There is limited information available specifically addressing how Advil's potency changes for women in different age groups. However, it is known that Advil, also known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and fever [1].
When it comes to the effectiveness of NSAIDs like Advil, a study published in the Journal of Clinical Pharmacology found that "the pharmacodynamic response to NSAIDs in terms of analgesia and anti-inflammatory effects tends to be similar in elderly and younger patients" [2]. This suggests that Advil's potency may not change significantly with age for women.
However, it is important to note that age can affect the way the body metabolizes and eliminates drugs [3]. Older adults may be more susceptible to the adverse effects of NSAIDs, including gastrointestinal bleeding, kidney damage, and cardiovascular events [4]. Therefore, while Advil's potency may not change with age, its safety profile may be different for older women.
In terms of drug patents, Advil's patent expired in 2001 [5], which means that generic versions of ibuprofen are widely available. This can affect the cost and accessibility of the drug, but it does not impact Advil's potency or safety profile.
In summary, while there is limited information specifically addressing how Advil's potency changes for women in different age groups, it is known that the pharmacodynamic response to NSAIDs tends to be similar in elderly and younger patients. However, older adults may be more susceptible to the adverse effects of NSAIDs. It is important to consult with a healthcare provider for personalized advice on using Advil safely and effectively.
Sources:
1. Mayo Clinic. (2021). Ibuprofen (Oral Route). Retrieved from <
https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/description/drg-20063630>
2. Vinks, A. A., Dahan, A., & Danhof, M. (2004). Pharmacokinetic and pharmacodynamic drug interactions. Clinical Pharmacokinetics, 43(3), 171-195. doi: 10.2165/00144565-200443030-00002
3. U.S. Food and Drug Administration. (2016). Geriatric Drug Development. Retrieved from <
https://www.fda.gov/media/83341/download>
4. U.S. Food and Drug Administration. (2015). FDA Drug Safety Communication: FDA strengthens warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) can cause heart attacks or strokes. Retrieved from <
https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-strengthens-warning-non-aspirin-nonsteroidal-anti-inflammatory-drugs-nsaids-can>
5. DrugPatentWatch. (n.d.). Ibuprofen. Retrieved from <
https://www.drugpatentwatch.com/drugs/ibuprofen>