See the DrugPatentWatch profile for lipitor

Based on the available information, there is a connection between Lipitor, a medication used to treat high cholesterol, and exercise. According to a study published in the National Center for Biotechnology Information (NCBI) [3], exercise has been shown to enhance the effectiveness of Lipitor and other statins in lowering cholesterol levels.

The study explains that regular physical activity can increase the expression of LDL receptors in the liver, which are responsible for removing LDL (low-density lipoprotein) or "bad" cholesterol from the bloodstream [3]. This mechanism complements the action of Lipitor, which also works by increasing the number of LDL receptors in the liver [1].

Furthermore, another study published in the NCBI found that exercise can enhance the lipid-lowering effects of statins, including Lipitor, by reducing triglyceride levels and increasing HDL (high-density lipoprotein) or "good" cholesterol levels [2].

In summary, exercise has been shown to enhance the effectiveness of Lipitor in lowering cholesterol levels by increasing the expression of LDL receptors in the liver and improving lipid profiles.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://pubmed.ncbi.nlm.nih.gov/28807461/>
[3] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679305/>