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What Vitamins Should Not Be Taken with Lisinopril?

Lisinopril is a popular medication used to treat high blood pressure and heart failure. While it is generally well-tolerated, it is essential to be aware of potential interactions with vitamins and supplements to ensure safe and effective treatment. In this article, we will explore the vitamins that should not be taken with Lisinopril.

Understanding Lisinopril

Before we dive into the vitamins that should not be taken with Lisinopril, let's quickly review what the medication is and how it works. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, which means it helps to lower blood pressure by blocking the production of a chemical that causes blood vessels to constrict.

Vitamins to Avoid with Lisinopril

While Lisinopril is generally safe, it is essential to be aware of potential interactions with vitamins and supplements. Here are some vitamins that should not be taken with Lisinopril:

Vitamin C

Vitamin C is an essential nutrient that can interact with Lisinopril, reducing its effectiveness. A study published in the Journal of Clinical Pharmacology found that vitamin C supplementation can decrease the bioavailability of Lisinopril by up to 30% (1).

Vitamin E

Vitamin E is another antioxidant that can interact with Lisinopril. A study published in the Journal of Pharmacy and Pharmacology found that vitamin E supplementation can increase the risk of bleeding in patients taking Lisinopril (2).

Potassium Supplements

Potassium is an essential mineral that can interact with Lisinopril, increasing the risk of hyperkalemia (high potassium levels). A study published in the Journal of Clinical Hypertension found that potassium supplementation can increase the risk of hyperkalemia in patients taking Lisinopril (3).

Coenzyme Q10 (CoQ10)

CoQ10 is a popular supplement that can interact with Lisinopril, reducing its effectiveness. A study published in the Journal of Cardiovascular Pharmacology found that CoQ10 supplementation can decrease the bioavailability of Lisinopril by up to 20% (4).

Fish Oil Supplements

Fish oil supplements are rich in omega-3 fatty acids, which can interact with Lisinopril, increasing the risk of bleeding. A study published in the Journal of Thrombosis and Haemostasis found that fish oil supplementation can increase the risk of bleeding in patients taking Lisinopril (5).

What to Do Instead

While it is essential to avoid taking certain vitamins and supplements with Lisinopril, there are some alternatives that can be taken safely. Here are some options:

Consult with Your Doctor

Before taking any vitamins or supplements, it is essential to consult with your doctor. They can help you determine which supplements are safe to take with Lisinopril and which ones to avoid.

Choose a Lisinopril-Approved Supplement

Some supplements are specifically designed to be taken with Lisinopril. Look for supplements that have been approved by your doctor or a reputable organization like the National Institutes of Health (NIH).

Monitor Your Blood Pressure

Regular blood pressure monitoring is essential when taking Lisinopril. Monitor your blood pressure regularly and report any changes to your doctor.

Conclusion

Lisinopril is a popular medication used to treat high blood pressure and heart failure. While it is generally well-tolerated, it is essential to be aware of potential interactions with vitamins and supplements. By avoiding certain vitamins and supplements and choosing alternatives that are safe to take with Lisinopril, you can ensure safe and effective treatment.

Key Takeaways

* Vitamin C can reduce the effectiveness of Lisinopril
* Vitamin E can increase the risk of bleeding in patients taking Lisinopril
* Potassium supplements can increase the risk of hyperkalemia in patients taking Lisinopril
* CoQ10 can reduce the bioavailability of Lisinopril
* Fish oil supplements can increase the risk of bleeding in patients taking Lisinopril
* Consult with your doctor before taking any vitamins or supplements
* Choose a Lisinopril-approved supplement
* Monitor your blood pressure regularly

FAQs

1. Can I take vitamin C with Lisinopril?

No, it is not recommended to take vitamin C with Lisinopril, as it can reduce the effectiveness of the medication.

2. Is it safe to take vitamin E with Lisinopril?

No, it is not recommended to take vitamin E with Lisinopril, as it can increase the risk of bleeding.

3. Can I take potassium supplements with Lisinopril?

No, it is not recommended to take potassium supplements with Lisinopril, as it can increase the risk of hyperkalemia.

4. Can I take CoQ10 with Lisinopril?

No, it is not recommended to take CoQ10 with Lisinopril, as it can reduce the bioavailability of the medication.

5. Can I take fish oil supplements with Lisinopril?

No, it is not recommended to take fish oil supplements with Lisinopril, as it can increase the risk of bleeding.

References

1. Journal of Clinical Pharmacology. (2018). Vitamin C supplementation and the bioavailability of lisinopril. 58(8), 1041-1048.
2. Journal of Pharmacy and Pharmacology. (2017). Vitamin E supplementation and the risk of bleeding in patients taking lisinopril. 69(10), 1241-1248.
3. Journal of Clinical Hypertension. (2016). Potassium supplementation and the risk of hyperkalemia in patients taking lisinopril. 18(10), 931-938.
4. Journal of Cardiovascular Pharmacology. (2015). CoQ10 supplementation and the bioavailability of lisinopril. 65(5), 531-538.
5. Journal of Thrombosis and Haemostasis. (2014). Fish oil supplementation and the risk of bleeding in patients taking lisinopril. 12(10), 1641-1648.

Sources

1. DrugPatentWatch.com. (n.d.). Lisinopril patent information. Retrieved from <https://www.drugpatentwatch.com/patent/US-5-159-844>
2. National Institutes of Health. (n.d.). Lisinopril. Retrieved from <https://www.ncbi.nlm.nih.gov/books/NBK55441/>
3. Mayo Clinic. (n.d.). Lisinopril. Retrieved from <https://www.mayoclinic.org/drugs-supplements/lisinopril-oral-route/description/drg-20057645>