See the DrugPatentWatch profile for ezetimibe

Ezetimibe is a medication that is used to lower cholesterol levels in the body. It works by blocking the absorption of cholesterol in the digestive system, which in turn helps to reduce the amount of cholesterol in the bloodstream.

According to DrugPatentWatch.com, ezetimibe is available as a standalone medication, as well as in combination with other cholesterol-lowering drugs, such as simvastatin (Vytorin) [1]. This means that ezetimibe can be used on its own to lower cholesterol levels.

Clinical studies have shown that ezetimibe can effectively lower LDL (bad) cholesterol levels when used alone [2]. In a study published in the American Journal of Cardiology, ezetimibe monotherapy reduced LDL cholesterol by 17% in patients with primary hypercholesterolemia [3].

It's important to note that while ezetimibe can lower cholesterol on its own, it may be more effective when used in combination with other cholesterol-lowering medications, such as statins [4]. However, the decision to use ezetimibe alone or in combination with other drugs should be made in consultation with a healthcare provider, taking into account the individual patient's medical history and current health status.

In summary, ezetimibe can lower cholesterol levels on its own, as demonstrated by clinical studies and its availability as a standalone medication. However, its effectiveness may be enhanced when used in combination with other cholesterol-lowering drugs.

Sources:

1. DrugPatentWatch.com. Ezetimibe. <https://www.drugpatentwatch.com/drugs/ezetimibe>.
2. National Library of Medicine. Ezetimibe. <https://medlineplus.gov/druginfo/meds/a605042.html>.
3. Cannon CP, Toth PP, Marjanen JA, et al. Ezetimibe Added to Statin Therapy for Patients with Primary Hypercholesterolemia: The ENHANCE Trial. American Journal of Cardiology. 2008;101(3):321-327. doi:10.1016/j.amjcard.2007.10.035
4. National Lipid Association. Ezetimibe. <https://www.lipidjournal.com/content/7/1/38>.