See the DrugPatentWatch profile for benadryl

Benadryl, also known as diphenhydramine, is an antihistamine medication used to treat allergies, insomnia, and motion sickness. According to the U.S. National Library of Medicine, Benadryl is broken down in the liver by enzymes, but there is no clear evidence that it has a significant effect on liver function [1]. However, it is important to note that Benadryl can interact with other medications that are metabolized in the liver, potentially increasing the risk of liver damage [2].

It is always recommended to consult with a healthcare professional or pharmacist before starting any new medication, especially for individuals with pre-existing liver conditions or those taking other medications that affect liver function. They can provide personalized advice based on an individual's medical history and current medications.

In summary, Benadryl does not have a significant effect on liver function in healthy individuals, but it can interact with other medications that are metabolized in the liver. It is always best to consult with a healthcare professional before starting any new medication.

Sources:

[1] U.S. National Library of Medicine. (2021). Diphenhydramine. Retrieved from <https://medlineplus.gov/druginfo/meds/a682033.html>.

[2] DrugPatentWatch. (2021). Benadryl. Retrieved from <https://www.drugpatentwatch.com/drugs/benadryl>.