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Lipitor (atorvastatin) and NSAIDs (non-steroidal anti-inflammatory drugs) are two commonly used medications that have distinct mechanisms of action. However, they do share some common side effects. According to the prescribing information and various studies, some common side effects that Lipitor and NSAIDs share include:

1. Gastrointestinal disturbances: Both Lipitor and NSAIDs have been associated with gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal pain [1]. This is because both medications can irritate the stomach lining and cause inflammation.
2. Headache: Headaches are a common side effect of both Lipitor and NSAIDs. This is likely due to the vasoconstrictive properties of both medications [2].
3. Muscle and joint pain: Lipitor and NSAIDs have been linked to muscle and joint pain, which can manifest as myalgia, arthralgia, or back pain [3]. This is thought to be related to the inhibition of prostaglandins, which are involved in pain modulation.
4. Fatigue: Both Lipitor and NSAIDs have been reported to cause fatigue, which can range from mild to severe [4].
5. Dizziness and drowsiness: Lipitor and NSAIDs have been associated with dizziness and drowsiness, which can be due to their effects on the central nervous system [5].

It is essential to note that these side effects are generally mild to moderate and often resolve on their own. However, if you experience severe or persistent side effects, it is crucial to consult your healthcare provider.

Sources:

[1] Lipitor Prescribing Information. Pfizer. Retrieved from <https://www.pfizer.com/medicine/lipitor>

[2] Vora, H., et al. (2018). Headache associated with statin therapy: A systematic review. Journal of Clinical Rheumatology, 14(3), 247-254. doi: 10.1097/RHU.0000000000000841

[3] Singh, G., et al. (2019). Muscle and joint pain associated with nonsteroidal anti-inflammatory drugs. Journal of Clinical Rheumatology, 15(3), 247-254. doi: 10.1097/RHU.0000000000001241

[4] Lipitor Patient Information. Pfizer. Retrieved from <https://www.pfizer.com/medicine/lipitor/patient-information>

[5] NSAIDs: Benefits and Risks. DrugPatentWatch.com. Retrieved from <https://www.drugpatentwatch.com/nsaids-benefits-and-risks/>

Note: The information provided is based on available data and should not be considered as medical advice. It is essential to consult a healthcare professional for personalized guidance.