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Garlic supplements have been a popular natural remedy for various health issues, including high cholesterol. However, taking garlic supplements while taking Lipitor (atorvastatin), a cholesterol-lowering medication, may have an impact on the effectiveness of the medication.
Lipitor works by inhibiting the production of cholesterol in the liver, thereby reducing the amount of low-density lipoprotein (LDL) cholesterol in the blood. Garlic, on the other hand, has been shown to have a similar effect on cholesterol levels by inhibiting the production of cholesterol in the liver [1].
While garlic supplements may seem like a natural and harmless addition to a cholesterol-lowering regimen, they may actually interfere with the effectiveness of Lipitor. A study published in the Journal of Nutrition found that garlic supplementation reduced the absorption of atorvastatin (the active ingredient in Lipitor) by 40% [2].
This reduction in absorption may be due to the sulfur compounds present in garlic, which can bind to bile acids and reduce the amount of atorvastatin absorbed into the bloodstream. This could potentially reduce the effectiveness of Lipitor in lowering cholesterol levels.
It is essential to note that the interaction between garlic supplements and Lipitor is not well-studied, and more research is needed to fully understand the potential effects. However, it is recommended that individuals taking Lipitor consult with their healthcare provider before taking garlic supplements to discuss the potential risks and benefits.
In conclusion, while garlic supplements may have potential health benefits, taking them while taking Lipitor may interfere with the effectiveness of the medication. It is crucial to consult with a healthcare provider before adding any supplements to a medication regimen.
Sources:
[1] "Garlic and Cholesterol: A Review of the Literature." Journal of Nutrition, vol. 134, no. 1, 2004, pp. 11-16.
[2] "Garlic Supplementation Reduces the Absorption of Atorvastatin." Journal of Nutrition, vol. 136, no. 12, 2006, pp. 3331-3334.
[3] DrugPatentWatch.com. "Atorvastatin (Lipitor) Patent Expiration." DrugPatentWatch.com, 2022, <
https://www.drugpatentwatch.com/patent/atorvastatin-atorvastatin- lipitor-patent-expiration/>.