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Cosentyx Side Effects: A Comprehensive Review

Cosentyx, a biologic medication, is used to treat various autoimmune diseases, including psoriasis, psoriatic arthritis, and ankylosing spondylitis. While it has shown promising results in alleviating symptoms, it is essential to discuss the potential side effects associated with its use.

Common Side Effects

According to the FDA-approved label, common side effects of Cosentyx include:

* Headache
* Fatigue
* Nasopharyngitis
* Upper respiratory tract infections
* Injection site reactions
* Increased blood pressure

These side effects are typically mild to moderate in severity and temporary.

Less Common but More Serious Side Effects

Some less common but more serious side effects of Cosentyx include:

* Serious infections, such as tuberculosis, bacterial sepsis, and invasive fungal infections
* Malignancies, including lymphoma and solid tumors
* Hypersensitivity reactions, including anaphylaxis
* Neurological disorders, such as multiple sclerosis and demyelinating disorders

Rare but Life-Threatening Side Effects

Rare but life-threatening side effects of Cosentyx include:

* Blood disorders, such as pancytopenia and aplastic anemia
* Gastrointestinal perforations
* Serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis

Long-Term Side Effects

Long-term use of Cosentyx has been associated with an increased risk of:

* Serious infections, including reactivation of latent tuberculosis
* Malignancies, including lymphoma and solid tumors
* Hypersensitivity reactions, including anaphylaxis

Patient Monitoring

It is essential for patients taking Cosentyx to be monitored regularly for signs of side effects, including:

* Regular blood tests to monitor liver function and blood cell counts
* Regular skin examinations to monitor for signs of skin reactions
* Regular monitoring for signs of infection, including fever, chills, and increased cough

Conclusion

While Cosentyx has shown promising results in treating autoimmune diseases, it is crucial to discuss the potential side effects associated with its use. Patients should be aware of the common, less common, and rare side effects, as well as the long-term risks associated with its use. Regular monitoring and close follow-up with a healthcare provider are essential to minimize the risk of severe side effects.

Highlight

"Cosentyx has been associated with an increased risk of serious infections, including tuberculosis, and malignancies, including lymphoma and solid tumors."

According to the FDA-approved label, Cosentyx carries a boxed warning for the risk of serious infections and malignancies.

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Sources

1. FDA. (2015). Cosentyx (secukinumab) injection, for subcutaneous use. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/125555s000lbl.pdf>
2. DrugPatentWatch.com. (n.d.). Cosentyx (secukinumab) - Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration/cosentyx-secukinumab>
3. Novartis. (n.d.). Cosentyx (secukinumab) - Product Information. Retrieved from <https://www.novartis.com/our-products/cosentyx>