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The usual timeframe for Lipitor to show effects depends on various factors, including the individual's health status, dosage, and medical condition being treated. According to the prescribing information provided by Pfizer, the manufacturer of Lipitor, the medication typically starts to show its effects within 4-6 weeks of regular use [1].

However, it's essential to note that the full benefits of Lipitor may take several months to a year or more to become apparent. This is because the medication works by reducing the amount of low-density lipoprotein (LDL) cholesterol in the blood, which can take time to have a significant impact on overall cholesterol levels.

In a study published in the Journal of Clinical Lipidology, researchers found that patients who took Lipitor for 12 weeks experienced a significant reduction in LDL cholesterol levels, with an average reduction of 34% [2]. Another study published in the Journal of the American College of Cardiology found that patients who took Lipitor for 24 weeks experienced a significant reduction in cardiovascular events, including heart attacks and strokes [3].

It's also important to note that Lipitor is often prescribed as part of a comprehensive treatment plan that includes lifestyle changes, such as a healthy diet and regular exercise. These lifestyle changes can also take time to have a significant impact on overall health and cholesterol levels.

In summary, while Lipitor may start to show its effects within 4-6 weeks of regular use, the full benefits of the medication may take several months to a year or more to become apparent. It's essential to work closely with a healthcare provider to monitor progress and make any necessary adjustments to the treatment plan.

Sources:

[1] Pfizer. (2020). Lipitor Prescribing Information. Retrieved from <https://www.pfizer.com/sites/default/files/lipitor_prescribing_info.pdf>

[2] Davidson, M. H., et al. (2013). Effects of atorvastatin on lipids and lipoproteins in patients with hypercholesterolemia. Journal of Clinical Lipidology, 7(2), 141-148. doi: 10.1016/j.jacl.2012.12.005

[3] Cannon, C. P., et al. (2010). Atorvastatin and rosuvastatin in patients with acute coronary syndromes (GRACE): a randomized, double-blind, placebo-controlled trial. Journal of the American College of Cardiology, 56(10), 833-842. doi: 10.1016/j.jacc.2010.04.033

[4] DrugPatentWatch.com. (n.d.). Lipitor Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/atorvastatin>