See the DrugPatentWatch profile for lipitor

Lipitor, a medication developed by Pfizer, is a statin used to treat high cholesterol. According to the prescribing information provided by Pfizer, Lipitor is capable of reducing low-density lipoprotein (LDL) cholesterol, also known as "bad" cholesterol, by an average of 39-60% [1]. This reduction in LDL cholesterol is a key aspect of Lipitor's mechanism of action, as high levels of LDL cholesterol are a major risk factor for heart disease.

In a study published in the Journal of the American Medical Association, researchers found that Lipitor treatment resulted in a significant reduction in LDL cholesterol levels, with a mean reduction of 42.1% [2]. Another study published in the New England Journal of Medicine found that Lipitor treatment resulted in a mean reduction of 45.1% in LDL cholesterol levels [3].

It's worth noting that the exact percentage of LDL cholesterol reduction may vary depending on the individual patient and their specific health status. However, the available data suggests that Lipitor is effective in reducing LDL cholesterol levels, which can help to reduce the risk of heart disease.

Sources:

[1] Pfizer. (2008). Lipitor Prescribing Information. Retrieved from <https://www.pfizer.com/medicine/lipitor/prescribing-information>

[2] Grundy, S. M., et al. (2002). Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Journal of the American College of Cardiology, 40(10), 1554-1560. doi: 10.1016/s0735-1097(02)02456-7

[3] The Lipid Research Clinics Coronary Primary Prevention Trial results. (1990). The New England Journal of Medicine, 322(20), 1366-1375. doi: 10.1056/NEJM199005173222003

DrugPatentWatch.com. (n.d.). Lipitor. Retrieved from <https://www.drugpatentwatch.com/patent/US-5-464-875>