See the DrugPatentWatch profile for aspirin
Based on the information available, it is difficult to definitively state that daytime aspirin doses are safer as safety can depend on various factors such as the individual's health condition, the dosage, and the frequency of use. However, some studies suggest that taking aspirin at night might have certain advantages.
A study published in the journal "Heart" found that taking aspirin before bedtime could provide better protection against heart attacks [1]. This is because the risk of heart attack is higher in the early morning hours, and aspirin's anti-clotting effect is strongest 10-12 hours after ingestion. Therefore, taking aspirin at night allows the drug to reach its peak effect in the morning when the risk is highest.
As for daytime doses, it's important to note that aspirin can have side effects, including stomach ulcers and bleeding, especially with long-term use or in high doses [2]. Therefore, it's crucial to follow the recommended dosage and consult with a healthcare provider before starting or changing an aspirin regimen.
In terms of patent information, DrugPatentWatch.com lists several patents related to aspirin, including methods of use and formulations [3]. However, these listings do not provide specific information on the safety of daytime versus nighttime doses.
In conclusion, while some studies suggest that taking aspirin at night might have certain advantages, it is not universally true that daytime aspirin doses are safer. The safety of aspirin use depends on various factors, and it's essential to follow medical advice and the recommended dosage.
Sources:
[1] "Aspirin before bed 'better for heart attack prevention'" - BBC News, Feb 2019,
https://www.bbc.com/news/health-47184024
[2] "Aspirin: Uses, Side Effects, Interactions, Dosage, and Warning" - WebMD,
https://www.webmd.com/vitamins/ai/ingredientmono-971/aspirin
[3] "Aspirin" - DrugPatentWatch.com,
https://www.drugpatentwatch.com/drugs/aspirin
(Note: The above sources were accessed on March 2, 2023)