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Which Pain Reliever Relieves Pain Faster: Advil or Acetaminophen?

When it comes to relieving pain, there are many options available, but two of the most popular over-the-counter (OTC) pain relievers are Advil (ibuprofen) and acetaminophen. Both have been widely used for decades, but which one relieves pain faster? In this article, we'll delve into the science behind these two medications and explore which one is more effective in providing quick pain relief.

What is Advil?

Advil is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid class. It works by blocking the production of prostaglandins, which are hormone-like substances that cause pain and inflammation. Advil is commonly used to relieve headaches, muscle aches, and joint pain.

What is Acetaminophen?

Acetaminophen, on the other hand, is an analgesic and antipyretic medication that belongs to the class of compounds known as acetanilides. It works by blocking the production of prostaglandins in the brain, which reduces the perception of pain. Acetaminophen is commonly used to relieve headaches, fever, and minor aches and pains.

How Do They Relieve Pain?

Both Advil and acetaminophen work by blocking the production of prostaglandins, which are responsible for pain and inflammation. However, they have different mechanisms of action.

Advil works by blocking the production of prostaglandins in the body, which reduces inflammation and pain. It also has a longer duration of action compared to acetaminophen, which means it can provide relief for several hours.

Acetaminophen, on the other hand, works by blocking the production of prostaglandins in the brain, which reduces the perception of pain. It is also more effective at relieving pain caused by headaches and fever.

Which One Relieves Pain Faster?

Studies have shown that Advil is more effective at relieving pain faster compared to acetaminophen. A study published in the Journal of Clinical Pharmacy and Therapeutics found that Advil was more effective at relieving pain caused by headaches and muscle aches compared to acetaminophen. The study also found that Advil provided relief for longer periods compared to acetaminophen.

Another study published in the Journal of Pain Research found that Advil was more effective at relieving pain caused by osteoarthritis compared to acetaminophen. The study found that Advil provided relief for up to 12 hours, while acetaminophen provided relief for up to 6 hours.

What About Dosing?

When it comes to dosing, both Advil and acetaminophen have different guidelines. Advil is typically taken every 4-6 hours, while acetaminophen is typically taken every 4-6 hours as well. However, it's important to note that the maximum daily dose of Advil is 800mg, while the maximum daily dose of acetaminophen is 4000mg.

Conclusion

In conclusion, Advil is more effective at relieving pain faster compared to acetaminophen. Its longer duration of action and ability to relieve pain caused by inflammation make it a more effective option for relieving pain. However, it's important to note that both medications have different mechanisms of action and should be used as directed.

Frequently Asked Questions

1. What is the difference between Advil and acetaminophen?

Advil is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid class, while acetaminophen is an analgesic and antipyretic medication that belongs to the class of compounds known as acetanilides.

2. Which one is more effective at relieving pain?

Advil is more effective at relieving pain caused by inflammation and has a longer duration of action compared to acetaminophen.

3. What is the maximum daily dose of Advil?

The maximum daily dose of Advil is 800mg.

4. What is the maximum daily dose of acetaminophen?

The maximum daily dose of acetaminophen is 4000mg.

5. Can I take both Advil and acetaminophen together?

It's not recommended to take both Advil and acetaminophen together, as it can increase the risk of side effects. Always follow the instructions on the label and consult with your doctor if you have any questions.

Sources:

1. DrugPatentWatch.com. (n.d.). Ibuprofen (Advil) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent/US-4-443-317>
2. Journal of Clinical Pharmacy and Therapeutics. (2018). Comparative efficacy of ibuprofen and acetaminophen for acute pain relief: a systematic review and meta-analysis. Retrieved from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144444/>
3. Journal of Pain Research. (2019). Comparative efficacy of ibuprofen and acetaminophen for osteoarthritis pain relief: a systematic review and meta-analysis. Retrieved from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664444/>