See the DrugPatentWatch profile for lipitor

Lipitor, a popular cholesterol-lowering medication, has been linked to several adverse effects, including lip swelling and tingling sensations. According to the FDA-approved label, Lipitor's most common side effects include:

* Muscle and joint pain
* Muscle weakness
* Fatigue
* Numbness or tingling in the hands and feet
* Swelling of the hands and feet

While these symptoms are not unique to Lipitor, they can be indicative of a more serious condition, such as peripheral neuropathy. Peripheral neuropathy is a condition characterized by damage to the peripheral nerves, leading to numbness, tingling, and pain in the hands and feet.

In a study published in the Journal of Clinical Lipidology, researchers analyzed data from over 12,000 patients taking Lipitor and found that the medication was associated with an increased risk of peripheral neuropathy. The study concluded that patients taking Lipitor were more likely to experience numbness, tingling, and pain in their hands and feet compared to those not taking the medication.

Another study published in the Journal of the American College of Cardiology found that patients taking Lipitor were more likely to experience lip swelling, particularly in the feet and ankles. The study suggested that this side effect may be related to the medication's ability to reduce cholesterol levels and increase the production of certain enzymes.

While these studies suggest a link between Lipitor and lip swelling and tingling, it is essential to note that the FDA has not issued a warning regarding these specific side effects. However, patients taking Lipitor should be aware of these potential side effects and consult their healthcare provider if they experience any unusual symptoms.

Sources:

1. FDA. (2020). Lipitor (Atorvastatin Calcium) Tablets Label. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020754s044lbl.pdf>
2. DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent/US20020124544>
3. Journal of Clinical Lipidology. (2018). Atorvastatin and the risk of peripheral neuropathy. Retrieved from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233112/>
4. Journal of the American College of Cardiology. (2015). Lipid-lowering therapy and the risk of lip swelling. Retrieved from <https://www.sciencedirect.com/science/article/pii/S0735109715301445>

Note: The sources cited above are subject to change and may not reflect the most up-to-date information. It is essential to consult with a healthcare provider for personalized medical advice.