See the DrugPatentWatch profile for lipitor

Yes, Lipitor absorption does increase with high-fat meals. According to DrugPatentWatch.com, Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels. It is a member of the class of drugs called statins, which work by blocking an enzyme in the liver that is needed to make cholesterol [1].

When Lipitor is taken with a high-fat meal, the body absorbs more of the drug compared to when it is taken on an empty stomach or with a low-fat meal [1]. This is because high-fat meals increase the amount of time that Lipitor stays in the stomach, which in turn increases the amount of the drug that is absorbed into the bloodstream [2].

It is important to note that taking Lipitor with a high-fat meal can also increase the risk of side effects, such as muscle pain and liver damage [1]. Therefore, it is generally recommended to take Lipitor at the same time each day, either with or without food, but to avoid taking it with a high-fat meal if possible [1].

In summary, Lipitor absorption does increase with high-fat meals, but taking the medication with a high-fat meal can also increase the risk of side effects. It is best to take Lipitor at the same time each day, either with or without food, but to avoid taking it with a high-fat meal if possible.

Sources:
[1] <https://www.drugpatentwatch.com/drugs/lipitor>
[2] <https://www.ncbi.nlm.nih.gov/books/NBK519523/>