See the DrugPatentWatch profile for methotrexate

Based on the sources provided, there is no specific mention of age-based dosage adjustments for methotrexate. However, it is important to note that methotrexate dosage adjustments may be necessary based on various factors such as the specific condition being treated, the patient's overall health, and any potential drug interactions or comorbidities.

The first source, Drug Patent Watch, provides information about the patent status and expiration of methotrexate, but does not specifically address dosage adjustments based on age [1].

The second source, UpToDate, discusses the therapeutic use and toxicity of high-dose methotrexate but does not mention age-based dosage adjustments [2].

The third source, a study published in the National Center for Biotechnology Information (NCBI), focuses on the therapeutic use of methotrexate in rheumatoid arthritis but does not provide specific information about age-based dosage adjustments [3].

It is important to consult with a healthcare professional, such as a doctor or pharmacist, who can consider individual patient factors and provide personalized dosing recommendations for methotrexate based on age and other relevant factors.

In summary, while the sources provided do not specifically mention age-based dosage adjustments for methotrexate, it is crucial to consult with a healthcare professional for personalized dosing recommendations based on individual patient factors.

Sources:
[1] Drug Patent Watch. Methotrexate. Retrieved from https://www.drugpatentwatch.com/p/tradename/METHOTREXATE
[2] UpToDate. Therapeutic use and toxicity of high-dose methotrexate. Retrieved from https://www.uptodate.com/contents/therapeutic-use-and-toxicity-of-high-dose-methotrexate
[3] National Center for Biotechnology Information (NCBI). Methotrexate in Rheumatoid Arthritis: A Quarter Century of Development. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015755/