See the DrugPatentWatch profile for lipitor

Yes, Lipitor (atorvastatin) has been associated with muscle pain and weakness, a condition known as myalgia, in some patients. According to the Lipitor medication guide provided by the FDA, "stop taking Lipitor if you have muscle pain, tenderness, or weakness that cannot be explained" [1].

The Lipitor drug label also includes information about myopathy and rhabdomyolysis, which are more severe forms of muscle damage that can occur with statin use, including Lipitor [2].

A study published in the American Journal of Cardiovascular Drugs found that "the most common adverse events associated with statin therapy are myalgia and myopathy" [3].

It is important to note that while muscle pain and weakness can be a side effect of Lipitor, these symptoms can also be caused by other medical conditions. If you experience muscle pain or weakness while taking Lipitor, it is important to speak with your healthcare provider to determine the cause and appropriate course of action.

In summary, based on the available information, Lipitor can cause muscle pain or weakness over time, and it is important for patients to be aware of this potential side effect and to speak with their healthcare provider if they experience muscle-related symptoms while taking the medication.

Sources:

1. [FDA. Lipitor Medication Guide](https://www.fda.gov/media/74230/download)
2. [FDA. Lipitor Label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s054,021132s016,021183s010,021241s005lbl.pdf)
3. [American Journal of Cardiovascular Drugs. Muscle-related adverse events of statins: a systematic review](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173801/)
4. [DrugPatentWatch.com. Lipitor (Atorvastatin)](https://www.drugpatentwatch.com/drugs/lipitor)