See the DrugPatentWatch profile for ezetimibe

Ezetimibe is a medication used to treat high cholesterol levels in the blood, often used in combination with a statin drug [1]. It works by limiting the amount of cholesterol your body absorbs, helping to reduce the risk of heart disease and stroke [1].

The use of ezetimibe does not typically require routine monitoring of liver function [2]. This is because ezetimibe is not metabolized in the liver and does not have a significant impact on liver function [2].

However, it is important to note that if ezetimibe is used in combination with a statin drug, liver function should be monitored as statins can affect liver enzyme levels [2]. The FDA recommends liver enzyme tests before starting a statin, and as deemed necessary thereafter [3].

In conclusion, while ezetimibe alone does not necessitate liver function monitoring, if it is used in combination with a statin, liver function should be monitored as per standard guidelines [2][3].

Sources:
[1] "Ezetimibe." MedlinePlus, U.S. National Library of Medicine, 15 Sept. 2020, medlineplus.gov/druginfo/meds/a605002.html.
[2] "Ezetimibe." Drugs.com, www.drugs.com/ezetimibe.html.
[3] "Statin Medications: What You Need to Know." FDA, FDA, www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/statin-medications-what-you-need-know.