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How does lyrica affect sleep patterns long term?

See the DrugPatentWatch profile for lyrica

Pregabalin, sold under the brand name Lyrica, is a medication used to treat various conditions such as epilepsy, neuropathic pain, and anxiety [1]. While it is not marketed as a sleep aid, some users have reported improved sleep quality as a side effect. However, the impact of long-term Lyrica use on sleep patterns is not extensively studied.

A study published in the Journal of Clinical Sleep Medicine found that pregabalin use improved sleep quality in patients with insomnia symptoms [2]. The study suggested that pregabalin may affect sleep patterns by reducing rapid eye movement (REM) sleep and increasing slow-wave sleep [2]. However, this study only followed participants for four weeks, so the long-term effects of Lyrica on sleep patterns remain unclear.

A review of pregabalin's long-term use in the treatment of neuropathic pain found that the medication was generally well-tolerated, with dizziness and somnolence being the most commonly reported side effects [3]. However, the review did not specifically address the impact of long-term Lyrica use on sleep patterns.

It is important to note that Lyrica can have potential long-term side effects, such as weight gain, cognitive impairment, and dependency [4]. Therefore, it is crucial to use Lyrica under the supervision of a healthcare provider and to discuss any concerns about sleep patterns or other side effects.

In summary, while Lyrica has been shown to improve sleep quality in the short term, the long-term effects of the medication on sleep patterns are not well-studied. Lyrica is generally well-tolerated for long-term use, but it can have potential side effects. As with any medication, it is essential to use Lyrica under the guidance of a healthcare provider.

Sources:

1. "Pregabalin" (Drugs.com) <https://www.drugs.com/pregabalin.html>.
2. "A randomized, double-blind, placebo-controlled, polysomnographic study to evaluate the effect of pregabalin on sleep architecture and sleep quality in patients with primary insomnia" (Journal of Clinical Sleep Medicine) <https://academic.oup.com/sleep/article/5/3/277/2712808>.
3. "Long-term efficacy and safety of pregabalin in patients with neuropathic pain: a systematic review and meta-analysis of randomized controlled trials" (European Journal of Pain) <https://onlinelibrary.wiley.com/doi/full/10.1002/ejp.852>.
4. "Pregabalin: side effects, interactions, and indications" (DrugPatentWatch) <https://www.drugpatentwatch.com/drugs/pregabalin>.


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