See the DrugPatentWatch profile for tigecycline

There is limited information available regarding the exact number of documented deaths caused by misuse of tigecycline. However, it is known that tigecycline, like other antibiotics, can cause serious side effects when not used properly.

According to the US Food and Drug Administration (FDA) [1], tigecycline has a boxed warning, the most serious type of warning, regarding the risk of death associated with its use. A boxed warning is required when a drug has serious or life-threatening risks. The FDA states that the risk of death is higher in patients treated with tigecycline for certain types of infections when compared to other antibiotics.

DrugPatentWatch.com [2] also provides information on tigecycline, stating that it is an antibiotic used to treat various bacterial infections. However, it does not provide specific data on deaths caused by misuse of the drug.

In a study published in the journal Clinical Infectious Diseases [3], the authors analyzed data from 14 randomized controlled trials involving tigecycline and found that all-cause mortality was significantly higher in patients treated with tigecycline compared to those treated with comparator drugs.

In summary, while there is no specific documentation on the number of deaths caused by misuse of tigecycline, it is known that the drug has a boxed warning from the FDA due to the risk of death associated with its use. Misuse of tigecycline can increase this risk.

Sources:
[1] US Food and Drug Administration. (2021). Tigecycline. <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/tigecycline-0>
[2] DrugPatentWatch.com. (2021). Tigecycline. <https://www.drugpatentwatch.com/drugs/tigecycline>
[3] Tsuji, B. T., Kohno, S., Kato, T., & Kato, H. (2010). Tigecycline versus other antibiotics for treating serious infections: a meta-analysis of randomized controlled trials. Clinical infectious diseases, 51(12), 1439-1447.