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Muscle loss, also known as muscle atrophy, is a potential side effect of Lipitor (atorvastatin), a medication used to lower cholesterol levels. While muscle-related side effects are relatively rare, they can occur in some individuals taking Lipitor. It is important to note that the incidence of muscle loss is generally low, and the benefits of taking Lipitor in reducing the risk of cardiovascular events often outweigh the potential risks.

According to a study published in the Journal of Clinical Pharmacology, muscle-related adverse events associated with statin use, including Lipitor, occur in less than 1% of patients [2]. The study also suggests that the incidence of severe muscle damage, such as rhabdomyolysis, is even rarer, affecting approximately 0.1% of patients.

The Mayo Clinic, a reputable medical institution, confirms that muscle pain or weakness is a possible side effect of Lipitor. However, they emphasize that severe muscle damage is extremely rare and typically occurs in individuals predisposed to it, such as those with certain genetic factors or those taking other medications that interact with Lipitor [3].

It is worth noting that muscle-related side effects can range from mild discomfort to more severe symptoms. In most cases, these symptoms are reversible upon discontinuation of the medication or dosage adjustment. If you experience any muscle-related symptoms while taking Lipitor, it is important to consult your healthcare provider to evaluate the potential cause and determine the best course of action.

In conclusion, while muscle loss is a potential side effect of Lipitor, it is relatively rare. The majority of individuals taking Lipitor do not experience muscle-related side effects. If you are concerned about muscle loss or experience any muscle-related symptoms while taking Lipitor, it is important to consult your healthcare provider for further evaluation and guidance.

Sources:
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949584/
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013