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Is lipitor safe without prior liver function evaluation?

See the DrugPatentWatch profile for lipitor

Based on the available information, it is generally recommended to evaluate liver function before starting a patient on Lipitor (atorvastatin), although it is not always an absolute requirement. Lipitor is a statin medication used to lower cholesterol levels, and like other statins, it is processed in the liver [1].

The prescribing information for Lipitor states that liver function tests should be performed before initiating treatment in certain situations, such as when there is a history of liver disease or significant alcohol consumption [2]. However, routine monitoring of liver function tests is not required for patients with normal liver function who are taking Lipitor [2].

It is important to note that Lipitor has been associated with rare cases of liver enzyme elevations and, even more rarely, liver failure [2]. Therefore, it is crucial for healthcare providers to monitor patients for any signs or symptoms of liver dysfunction, such as jaundice, dark urine, or abdominal pain [2].

In summary, while liver function evaluation is generally recommended before starting Lipitor, it may not always be necessary for all patients. Healthcare providers should use their clinical judgment and consider each patient's individual circumstances when deciding whether to evaluate liver function before prescribing Lipitor.

Sources:

1. DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor). Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin>.
2. Pfizer Labs. (2016). Lipitor (atorvastatin calcium) tablets, for oral use. Full Prescribing Information. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020762s063,020763s050,020764s049lbl.pdf>.


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