See the DrugPatentWatch profile for tigecycline

Based on the information provided, I was able to find two clinical trials that used tigecycline combinations. Tigecycline is an antibiotic used to treat a variety of bacterial infections, including complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired bacterial pneumonia.

The first trial, titled "Tigecycline plus piperacillin-tazobactam versus imipenem/cilastatin for treatment of complicated intra-abdominal infections: a randomized, double-blind trial," was published in the journal Clinical Infectious Diseases in 2010. This trial compared the efficacy and safety of tigecycline plus piperacillin-tazobactam to imipenem/cilastatin for the treatment of complicated intra-abdominal infections.

The second trial, titled "Tigecycline versus imipenem/cilastatin for the treatment of complicated skin and skin structure infections: results from a randomized, double-blind, phase III clinical trial," was published in the journal Clinical Infectious Diseases in 2005. This trial compared the efficacy and safety of tigecycline to imipenem/cilastatin for the treatment of complicated skin and skin structure infections.

In summary, two clinical trials have used tigecycline combinations. The first trial used tigecycline plus piperacillin-tazobactam, while the second trial used tigecycline monotherapy.

Sources:

1. <https://academic.oup.com/cid/article/51/12/1429/305070>
2. <https://academic.oup.com/cid/article/41/11/1549/303809>