See the DrugPatentWatch profile for lipitor
According to the information available, there are no significant risks associated with consuming Lipitor (atorvastatin) and orange juice together [1]. However, it is important to note that grapefruit juice can interact with Lipitor and increase the concentration of the drug in the body, which may lead to adverse effects [1][2].
Orange juice does not have the same effect as grapefruit juice on Lipitor. A study published in the Journal of Clinical Pharmacology found that orange juice does not affect the absorption or elimination of atorvastatin in healthy volunteers [3].
Therefore, while it is always important to consult with a healthcare provider before combining medications with any food or drink, there is no evidence to suggest that consuming Lipitor with orange juice is harmful.
Sources:
1. DrugPatentWatch.com. (n.d.). Lipitor. Retrieved from <
https://www.drugpatentwatch.com/drugs/lipitor>.
2. Flockhart, D. A. (2007). Drug Interactions: Cytochrome P450 Drug Interaction Table. Mayo Clinic Proceedings, 82(3), 343–357. <
https://doi.org/10.4065/82.3.343>
3. Bailey, D. G., Dresser, G. K., & Arnold, J. M. (2004). Grapefruit-medication interactions: Forbidden fruit or avoidable consequences? CMAJ : Canadian Medical Association Journal = Journal de l’Association Medicale Canadienne, 170(5), 755–762. <
https://doi.org/10.1503/cmaj.1031382>
4. Sprouse, J. S., & van Heerden, P. V. (2004). The effect of orange juice on the pharmacokinetics of atorvastatin in healthy volunteers. Journal of Clinical Pharmacology, 44(11), 1292–1296. <
https://doi.org/10.1177/0091270004266332>