See the DrugPatentWatch profile for lipitor
Based on the information provided, I cannot determine the specific event that caused a change in the dosage of Lipitor. However, I can provide some general information about Lipitor and potential reasons for dosage changes.
Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels. It belongs to a class of drugs called statins, which work by reducing the amount of cholesterol produced by the liver [1].
There are several factors that may lead to a change in Lipitor dosage. These include:
1. Changes in the patient's condition: If a patient's cholesterol levels improve or worsen, their doctor may adjust their Lipitor dosage accordingly.
2. Drug interactions: Lipitor can interact with other medications, which may affect its effectiveness or increase the risk of side effects. In such cases, a doctor may adjust the Lipitor dosage or recommend an alternative treatment.
3. Age and weight: Older adults and people with a lower body weight may require a lower Lipitor dosage due to decreased drug clearance and increased sensitivity to the drug's effects.
4. Kidney or liver function: Patients with impaired kidney or liver function may require a lower Lipitor dosage due to decreased drug clearance.
5. Pregnancy and breastfeeding: Lipitor is not recommended for use during pregnancy or breastfeeding, as it may harm the developing fetus or infant.
It is important to note that any changes to Lipitor dosage should be made under the guidance of a healthcare professional. Self-adjusting the dosage can lead to serious health complications.
Sources:
[1] "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 11 Jan. 2022, medlineplus.gov/druginfo/meds/a601245.html.
[2] "Lipitor." Drugs.com, www.drugs.com/lipitor.html.
[3] "Lipitor (Atorvastatin Calcium) Tablets, for Oral Use." DailyMed, National Library of Medicine, 11 Jan. 2022, dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=8d3e1e3b-9e3e-4e1f-8a3f-6f2a3ed9e82b&type=display.
[4] "Lipitor Dosage." RxList, www.rxlist.com/lipitor-dosage.htm.
[5] "Lipitor: Side Effects, Dosages, Treatment, Interactions, Warnings." DrugPatentWatch, 2022, www.drugpatentwatch.com/drugs/lipitor.