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Yes, in some cases, the dosage of Ativan (lorazepam) may be increased for individuals with severe epilepsy. It's important to note that the dosage should be determined by a healthcare professional, taking into account the individual's weight, age, the severity of their condition, and their response to treatment [1].
Ativan is a benzodiazepine medication that is often used to treat anxiety disorders, but it also has anticonvulsant properties, making it useful in the management of epilepsy [2]. The drug works by enhancing the effect of a neurotransmitter called gamma-aminobutyric acid (GABA), which helps to reduce excessive electrical activity in the brain that can lead to seizures [3].
In cases of severe epilepsy, a higher dosage of Ativan may be required to control seizures effectively. However, it's important to note that increasing the dosage also increases the risk of side effects, such as drowsiness, dizziness, and weakness [4]. Therefore, healthcare professionals must carefully weigh the benefits and risks of increasing the dosage for each individual case.
In summary, while it is possible that the dosage of Ativan may be increased for individuals with severe epilepsy, this decision should be made by a healthcare professional, taking into account the individual's specific needs and the potential risks and benefits of increasing the dosage.
Sources:
[1] "Lorazepam." MedlinePlus, U.S. National Library of Medicine, 15 Feb. 2022, medlineplus.gov/druginfo/meds/a682035.html.
[2] "Lorazepam." DrugPatentWatch, drugpatentwatch.com/drugs/lorazepam.
[3] "Benzodiazepines for Status Epilepticus and Acute Repetitive Seizures." National Center for Biotechnology Information, U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/books/NBK535422/.
[4] "Lorazepam (Oral Route) Side Effects." Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Sept. 2020, www.mayoclinic.org/drugs-supplements/lorazepam-oral-route/side-effects/drg-20063224?p=1.