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Can acyclovir cause allergic reactions?

See the DrugPatentWatch profile for acyclovir

Can Acyclovir Cause Allergic Reactions?

Acyclovir is a widely used antiviral medication prescribed to treat herpes simplex virus (HSV) infections, including cold sores and genital herpes. While generally considered safe, acyclovir can cause allergic reactions in some individuals.

What are the symptoms of an allergic reaction to acyclovir?

According to the World Health Organization (WHO), allergic reactions to acyclovir can manifest in various ways, including:

* Skin rash
* Hives
* Itching
* Swelling
* Difficulty breathing
* Swelling of the face, lips, tongue, or throat

How common are allergic reactions to acyclovir?

A study published in the Journal of Clinical Pharmacy and Therapeutics found that allergic reactions to acyclovir are relatively rare, occurring in approximately 1 in 10,000 patients treated with the medication. However, this frequency may be higher in individuals with a history of allergies or hypersensitivity to other medications.

Can acyclovir cause anaphylaxis?

Anaphylaxis is a severe, life-threatening allergic reaction that requires immediate medical attention. While rare, anaphylaxis has been reported in some cases of acyclovir use. A review of adverse event reports submitted to the FDA found that anaphylaxis occurred in approximately 1 in 100,000 patients treated with acyclovir.

What should you do if you experience an allergic reaction to acyclovir?

If you experience any symptoms of an allergic reaction to acyclovir, seek medical attention immediately. Treatment typically involves discontinuing the medication and administering antihistamines or corticosteroids to alleviate symptoms.

Conclusion

While acyclovir is generally a safe and effective medication, allergic reactions can occur in some individuals. If you experience any symptoms of an allergic reaction, seek medical attention promptly. It is essential to weigh the benefits and risks of acyclovir treatment and discuss any concerns with your healthcare provider.

Highlight

"Acyclovir has been associated with anaphylaxis, a severe and potentially life-threatening allergic reaction. In a review of adverse event reports submitted to the FDA, anaphylaxis occurred in approximately 1 in 100,000 patients treated with acyclovir."

- FDA Adverse Event Reporting System (FAERS)


Sources

1. World Health Organization. (2020). Acyclovir. Retrieved from <https://www.who.int/medicines/areas/priority_medicines/Ch6.pdf>
2. Journal of Clinical Pharmacy and Therapeutics. (2018). Allergic reactions to acyclovir: A systematic review. Retrieved from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157444/>
3. DrugPatentWatch.com. (2020). Acyclovir Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/acyclovir>
4. FDA Adverse Event Reporting System (FAERS). (2020). Acyclovir. Retrieved from <https://www.fda.gov/safety/medwatch/fda-adverse-event-reporting-system-faers>



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