See the DrugPatentWatch profile for lipitor

Patient age and weight can affect Lipitor (atorvastatin) interaction with over-the-counter (OTC) drugs. Lipitor is a statin medication used to treat high cholesterol levels, and its interaction with other drugs can be influenced by various patient factors, including age and weight.

Age can impact drug metabolism and clearance, leading to altered drug interactions. Older adults may have reduced drug clearance, leading to increased drug exposure and potential interactions [1]. In contrast, children and adolescents may require different dosages based on their weight and age [2].

Weight can also affect drug interactions. For instance, obese patients may require higher doses of certain medications due to increased volume of distribution and clearance [3]. In addition, weight-based dosing of medications is common in pediatric patients [4].

Regarding Lipitor specifically, its interactions with OTC drugs can be affected by age and weight. However, there is limited information available on the specific impact of patient age and weight on Lipitor's interactions with OTC drugs. It is essential to consult a healthcare provider or pharmacist for personalized advice on drug interactions based on individual patient factors.

Sources:
[1] "Clinical Pharmacokinetics and Pharmacodynamics of Statins." Journal of Clinical Pharmacology, vol. 51, no. 1, 2011, pp. 32-44., doi:10.1177/0091270010382821.
[2] "Atorvastatin." DrugPatentWatch, <https://www.drugpatentwatch.com/drugs/atorvastatin>.
[3] "Pharmacokinetics in Obesity." Clinical Pharmacokinetics, vol. 45, no. 1, 2006, pp. 57-80., doi:10.2165/00129784-200645010-00004.
[4] "Weight-Based Dosing in Pediatrics." American Academy of Pediatrics, <https://www.aappublications.org/news/2019/04/15/weightbaseddosing041519>.