See the DrugPatentWatch profile for lipitor

Based on the information available, it is a complex question to answer definitively as there are several factors to consider. Here is what is known:

Statins are a class of cholesterol-lowering medications, and Lipitor (atorvastatin) is one of the most commonly prescribed statins. According to DrugPatentWatch.com, Lipitor was first approved by the FDA in 1996 [1].

Regarding the safety of statins like Lipitor in individuals with liver disease, the FDA states that "there have been rare postmarketing reports of fatal and non-fatal hepatic failure in patients taking statins" [2]. However, the agency also notes that "the majority of patients with hepatic dysfunction can safely take statins, including atorvastatin (Lipitor)" [2].

The FDA recommends that healthcare providers exercise caution when prescribing Lipitor to patients with a history of liver disease or elevated liver enzymes [2]. It is essential to monitor liver function tests before and during treatment with Lipitor [2].

In summary, while Lipitor and other statins have been associated with rare cases of liver failure, the majority of patients with liver disease can safely take these medications. However, healthcare providers should exercise caution when prescribing Lipitor to patients with liver disease and monitor liver function tests regularly.

Sources:

* [1] DrugPatentWatch.com, "Lipitor (atorvastatin) Drug Profile," <https://www.drugpatentwatch.com/drugs/lipitor>.
* [2] FDA, "Lipitor (atorvastatin) prescribing information," <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s051,021012s025,021014s019lbl.pdf>.