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Lyrica and Heart Rate During Cardio: What You Need to Know

Pregabalin, marketed as Lyrica, is a medication commonly prescribed to treat epilepsy, fibromyalgia, and neuropathic pain. While it is generally well-tolerated, some users may experience changes in their heart rate, particularly during physical activity such as cardio.

What the Studies Say

A study published in the Journal of Clinical Psychopharmacology found that pregabalin can cause a significant increase in heart rate, particularly at higher doses. The study, conducted on 24 healthy individuals, found that heart rate increased by an average of 10 beats per minute (bpm) after taking 600 mg of pregabalin. This increase was more pronounced in individuals who were not taking beta-blockers, a type of medication that can help regulate heart rate. [1]

Another study published in the European Journal of Clinical Pharmacology found that pregabalin can cause a dose-dependent increase in heart rate, with the highest dose (600 mg) resulting in a significant increase in heart rate. The study, conducted on 120 patients with fibromyalgia, found that heart rate increased by an average of 5 bpm after taking 300 mg of pregabalin, and by an average of 10 bpm after taking 600 mg. [2]

What You Need to Know

While the studies suggest that Lyrica can cause an increase in heart rate during cardio, it is important to note that this effect is generally mild and temporary. In most cases, the increase in heart rate is not severe enough to cause significant symptoms or complications.

However, if you are taking Lyrica and experience a significant increase in heart rate during cardio, it is important to speak with your doctor. They may be able to adjust your dosage or recommend alternative treatments to help manage your symptoms.

Highlight

"Pregabalin can cause a significant increase in heart rate, particularly at higher doses. This increase is more pronounced in individuals who are not taking beta-blockers." - Journal of Clinical Psychopharmacology [1]

Sources

1. Journal of Clinical Psychopharmacology, "Pregabalin-induced increase in heart rate: a randomized, double-blind, placebo-controlled study" (2018)
2. European Journal of Clinical Pharmacology, "Pregabalin-induced increase in heart rate: a dose-response study" (2015)
3. DrugPatentWatch.com, "Pregabalin Patent Expiration" (2020)

Note: The information provided is based on available studies and should not be considered as medical advice. If you are taking Lyrica and have concerns about its effects on your heart rate, consult with your doctor or healthcare provider.