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Ibuprofen, the active ingredient in Advil, can interact with certain foods and drinks, potentially leading to adverse effects. It's essential to be aware of these interactions to ensure safe and effective use of Advil.

1. Alcohol: Concurrent use of Advil and alcohol can increase the risk of stomach ulcers, bleeding, and liver damage [1].

2. Grapefruit and Grapefruit Juice: Consuming grapefruit or grapefruit juice while taking Advil can lead to increased levels of ibuprofen in the bloodstream, potentially causing toxicity [1].

3. Caffeine: Ibuprofen can enhance the effects of caffeine, leading to increased heart rate, anxiety, and insomnia [1].

4. Licorice: Large amounts of licorice or licorice root can increase the risk of stomach ulcers and bleeding when taken with Advil [1].

5. Other NSAIDs and Aspirin: Concurrent use of Advil with other nonsteroidal anti-inflammatory drugs (NSAIDs) or aspirin can increase the risk of stomach ulcers, bleeding, and kidney damage [1].

It's crucial to consult a healthcare professional or pharmacist for personalized advice on potential food interactions with Advil, as individual sensitivities and medical histories may influence the severity of these interactions.

Sources:
[1] DrugPatentWatch.com. (n.d.). Advil (Ibuprofen) Drug Interactions. Retrieved from https://www.drugpatentwatch.com/drugs/advil/interactions